Mechanical Dyssynchrony Precedes QRS Widening in ATP‐Sensitive K + Channel–Deficient Dilated Cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Mechanical Dyssynchrony Precedes QRS Widening in ATP‐Sensitive K+ Channel–Deficient Dilated Cardiomyopathy
BACKGROUND Contractile discordance exacerbates cardiac dysfunction, aggravating heart failure outcome. Dissecting the genesis of mechanical dyssynchrony would enable an early diagnosis before advanced disease. METHODS AND RESULTS High-resolution speckle-tracking echocardiography was applied in a knockout murine surrogate of adult-onset human cardiomyopathy caused by mutations in cardioprotect...
متن کاملcorrelation between mitral regurgitation and myocardial mechanical dyssynchrony and qrs duration in patients with cardiomyopathy
background: several competing geometric and hemodynamic factors are suggested as contributing mechanisms for functional mitral regurgitation (mr) in heart failure patients. we aimed to study the relationships between the severity of mr and the qrs duration and dyssynchrony markers in patients with ischemic or dilated cardiomyopathy. methods: w e prospectively evaluated 251 heart failure patient...
متن کاملCorrelation between Mitral Regurgitation and Myocardial Mechanical Dyssynchrony and QRS Duration in Patients with Cardiomyopathy
BACKGROUND Several competing geometric and hemodynamic factors are suggested as contributing mechanisms for functional mitral regurgitation (MR) in heart failure patients. We aimed to study the relationships between the severity of MR and the QRS duration and dyssynchrony markers in patients with ischemic or dilated cardiomyopathy. METHODS We prospectively evaluated 251 heart failure patients...
متن کاملLeft ventricular diastolic mechanical dyssynchrony and associated clinical outcomes in children with dilated cardiomyopathy.
BACKGROUND We investigated diastolic mechanical dyssynchrony and its relation to clinical status in pediatric dilated cardiomyopathy (DCM). METHODS AND RESULTS We calculated a diastolic and systolic dyssynchrony index (standard deviation of time to peak tissue early diastolic/systolic velocity in 12 left ventricular segments) in 33 children with DCM and 46 control subjects. A threshold to dia...
متن کاملPrevalence of cardiac dyssynchrony and correlation with atrio-ventricular block and QRS width in dilated cardiomyopathy: an echocardiographic study
INTRODUCTION Cardiac dyssynchrony causes disorganised cardiac contraction, delayed wall contraction and reduced pumping efficiency. We aimed to assess the prevalence of different types of dyssynchrony in patients with dilated cardiomyopathy (DCM), and to establish the correlation between atrio-ventricular block and atrio-ventricular dyssynchrony (AVD), and between impaired intra-ventricular con...
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ژورنال
عنوان ژورنال: Journal of the American Heart Association
سال: 2013
ISSN: 2047-9980,2047-9980
DOI: 10.1161/jaha.113.000410